- The 16 teams still in contention will begin a new stage of the competition with eight high-profile matchups.
- The 25th edition of the CONMEBOL Sudamericana has delivered an outstanding level of competition so far, and the knockout stage promises to be no exception.
'La Gran Conquista' enters its decisive stage, with every team renewing its hopes with one clear objective: reaching the Final on November 21 at the Estadio Metropolitano Roberto Meléndez in Barranquilla, Colombia.
The CONMEBOL Sudamericana Round of 16 first legs promise excitement, color and unforgettable cup nights across the continent. The stage will begin on Tuesday with two matches, followed by three ties on Wednesday, before another three encounters on Thursday bring the opening leg of each matchup to a close.
Boca Juniors vs. Recoleta
Coming through the Playoffs, where they eliminated O'Higgins on penalties — with recent signing Montero saving Pavez's spot kick as Boca prevailed 4-3 — the Argentine side will look to make home advantage count in the first leg against Recoleta. Boca also have a strong record to draw on against Paraguayan opposition in the CONMEBOL Sudamericana. With Rodolfo Arruabarrena now in charge, they will aim to rediscover their traditional cup pedigree and build on the promising spells of football shown during the tie against the Chilean side.
Boca Juniors in the CONMEBOL Sudamericana 2026: results, squad and schedule
Recoleta travel to Argentina still unbeaten and will look to extend the strong run that saw them finish top of their group ahead of high-profile opponents and former South American champions such as Santos and San Lorenzo. Built around tactical discipline and defensive solidity, the Paraguayan side will aim to claim their second victory over Argentine opposition in this year's competition.
Recoleta in the CONMEBOL Sudamericana 2026: results, squad and schedule
Match details
Stadium: Alberto J. Armando ‘La Bombonera’, Buenos Aires.
Kick-off: Tuesday, August 11 - 7:00 p.m. (local time).
Referee: Piero Maza (CHI).
VAR: Juan Lara (CHI).
Match facts:
- Boca have progressed from each of their last seven knockout ties against Paraguayan teams in CONMEBOL competitions. More than half of those came in the CONMEBOL Sudamericana: they eliminated Cerro Porteño three times (2004, 2005 and 2014) and Deportivo Capiatá once (2014).
- In their first-ever participation in a CONMEBOL competition, Recoleta remain unbeaten in the CONMEBOL Sudamericana 2026 (1 win, 6 draws). Their only victory in the competition came away to an Argentine opponent: a 1-0 win over San Lorenzo on the final matchday of the Group Stage.
- Recoleta's Nelson Ferreira ranks third among goalkeepers for goals prevented so far in the CONMEBOL Sudamericana 2026, with 3.81. The Paraguayan goalkeeper recorded his highest save total in a single match in the competition last time out, making seven stops against San Lorenzo in Buenos Aires.
- Miguel Merentiel has scored Boca's last two goals in CONMEBOL competitions. The Uruguayan forward has four goals for 'El Xeneize' in these tournaments: all came in the first half, and three of them opened the scoring.
- Since joining Boca in 2024, Lautaro Blanco has recorded the most assists for 'El Xeneize' in CONMEBOL competitions, with six — three times as many as any other player on the list (Cristian Lema, Leandro Paredes and Kevin Zenón, with two each).
Bolívar vs. São Paulo
The Hernando Siles will host one of the most intriguing ties of the Round of 16, as Bolívar — fresh from eliminating Grêmio with two historic victories in the Playoffs — welcome São Paulo.
Their only previous meeting on Bolivian soil in a CONMEBOL knockout round ended in victory for the home side, a 4-3 win in the 2013 CONMEBOL Libertadores.
Bolívar in the CONMEBOL Sudamericana 2026: results, squad and schedule
The São Paulo side, who conceded the fewest goals in the Group Stage with just one, travel to Bolivia aiming to secure a result that will leave them in a strong position ahead of the return leg. 'Tricolor' also boast an impressive record in the current CONMEBOL Sudamericana: they are the only team that have not trailed at any point in their six matches so far.
São Paulo in the CONMEBOL Sudamericana 2026: results, squad and schedule
Match details
Stadium: Hernando Siles, La Paz.
Kick-off: Tuesday, August 11 - 8:30 p.m. (local time).
Referee: Wilmar Roldán (COL)
VAR: Keiner Jiménez (COL)
Match facts:
- This will be the fifth meeting between Bolívar and São Paulo in CONMEBOL competitions. Their only previous knockout tie came in the qualifying rounds of the 2013 Libertadores, when 'Tricolor' advanced 8-4 on aggregate after winning 5-0 in Brazil and losing 4-3 in Bolivia.
- Bolívar have never lost at home in the Round of 16 of a CONMEBOL competition, recording 14 wins in 17 matches (3 draws). Four of those victories came against Brazilian opposition, all in the Libertadores: 1-0 against Palmeiras in 1995, 2-1 against Santos in 2012, 3-1 against Athletico Paranaense in 2023 and 1-0 against Flamengo in 2024.
- Robson Matheus' last four goals for Bolívar in CONMEBOL competitions have all come against Brazilian opponents: he scored against Atlético Mineiro in 2025, struck twice against Fluminense last April and found the net in the most recent tie against Grêmio in the 2026 Sudamericana Playoffs.
- São Paulo are the only team that never trailed during the CONMEBOL Sudamericana 2026 Group Stage. 'Tricolor' spent almost the same amount of time level (298 minutes) as they did in front (294 minutes) during that phase.
- Artur, who has already scored twice for São Paulo in the CONMEBOL Sudamericana 2026, netted a brace in his most recent continental meeting with Bolívar. That came on the final matchday of the 2023 Libertadores Group Stage, when he was playing for Palmeiras in a 4-0 victory.
Red Bull Bragantino vs. Atlético Mineiro
Red Bull Bragantino and Atlético Mineiro will contest the only all-Brazilian tie in the CONMEBOL Sudamericana Round of 16, and it will also mark their first-ever meeting in a CONMEBOL competition. The Bragança side, with set pieces and aerial play among their main attacking weapons, will have the chance to make home advantage count before trying to complete the upset away in Belo Horizonte next week.
Red Bull Bragantino in the CONMEBOL Sudamericana 2026: results, squad and schedule
'Galo', coached by Argentine manager Eduardo Domínguez, come into the tie after winning their last two CONMEBOL Sudamericana matches without conceding and are also unbeaten in their last four domestic fixtures. Their Group Stage campaign showed they are a side that must be taken seriously.
Atlético Mineiro in the CONMEBOL Sudamericana 2026: results, squad and schedule
Match details
Stadium: Municipal Cícero de Souza Marques, Bragança Paulista.
Kick-off: Wednesday, August 12 - 7:00 p.m. (local time).
Referee: Leandro Rey (ARG).
VAR: Hernán Mastrángelo (ARG).
Match facts:
- Red Bull Bragantino and Atlético Mineiro have never faced each other in a CONMEBOL competition. Including Brazil's Série A, 'Braga' have won their last two meetings with 'Galo' without conceding, having previously recorded just one top-flight victory over the Belo Horizonte side since 1990 (20 matches - 1 win, 11 draws, 8 losses).
- Atlético Mineiro have won their last two CONMEBOL Sudamericana matches, keeping clean sheets in both (2-0 against Cienciano and 1-0 against Puerto Cabello). The only time they produced a longer winning run in the competition was between May and August 2019, when they won five consecutive matches, a sequence that included a Round of 16 tie against fellow Brazilian side Botafogo, as is again the case in this edition.
- RB Bragantino have scored more headed goals than any other team since the start of the CONMEBOL Sudamericana 2026, with five. Their two most recent goals of this type opened the scoring.
- Atlético Mineiro's Tomás Cuello has registered six assists in the CONMEBOL Sudamericana since 2024, four of them in this edition. Over that period, only Marcelino Moreno has more, with eight for Lanús, while Cuello is level with Juanfer Quintero, who has six for Racing and River.
- Atlético Mineiro recorded the fourth-best shot conversion rate during the CONMEBOL Sudamericana 2026 Group Stage, scoring with 12.7% of their attempts (8/63).
Tigre vs. Montevideo City Torque
The last time Tigre reached the Round of 16 of 'La Gran Conquista' was in 2012, when 'El Matador' went all the way to the Final. Riding the momentum of having come through the Playoffs — beating Nacional 3-0 in Uruguay before losing 2-1 at home — the Argentine side, with Ignacio Russo among the main figures in attack, will now face an opponent with a similarly ambitious approach.
Tigre in the CONMEBOL Sudamericana 2026: results, squad and schedule
Beyond their attacking style, Montevideo City Torque and Tigre were two of the three teams that spent the most minutes in front during the Group Stage. The Uruguayan side produced several high-level performances in a campaign that underlined the attacking quality they can display regardless of the context or venue. Diego Dabove vs. Marcelo Méndez: a tactical duel in Victoria.
Montevideo City Torque in the CONMEBOL Sudamericana 2026: results, squad and schedule
Match details
Stadium: José Dellagiovana, Buenos Aires.
Kick-off: Wednesday, August 12 - 7:00 p.m. (local time).
Referee: Ramón Abatti (BRA).
VAR: Rodolpho Toski (BRA).
Match facts:
- Tigre will contest the CONMEBOL Sudamericana Round of 16 for the second time. Their only previous appearance at this stage came in 2012, when they eliminated Deportivo Quito in the edition that ended with them reaching the Final against São Paulo.
- City Torque have the lowest defeat percentage among all teams to have played at least 15 matches in CONMEBOL Sudamericana history (13.3% - 9 wins, 4 draws, 2 losses). Their only two defeats both came away to Argentine opposition: 3-1 against Independiente in 2021 and 2-1 against Riestra in 2026.
- City Torque were one of four teams to score twice from direct attacks during the CONMEBOL Sudamericana 2026 Group Stage, alongside RB Bragantino, Botafogo and Santos.
- Tigre (2.26) and City Torque (2.23) ranked among the five teams that progressed the most metres up the pitch per second during the CONMEBOL Sudamericana 2026 Group Stage.
- Two of the three teams that spent the most minutes leading during the CONMEBOL Sudamericana 2026 Group Stage will face each other: City Torque (300) and Tigre (294).
Independiente Santa Fe vs. River Plate
Independiente Santa Fe showcased all of their attacking quality in the Playoffs against Caracas, with the evergreen Hugo Rodallega performing at an outstanding level. In the first leg in Bogotá, 'El Rojo' claimed a 2-0 victory with goals from Rodallega and Fagúndez. In the return leg in Venezuela, the Colombian side completed the job with a 3-0 win.
Santa Fe will now look for a victory that would allow them to make history: a win would give them four consecutive victories, equalling their best-ever winning streak in CONMEBOL competitions, last achieved in the 2013 CONMEBOL Libertadores.
Independiente Santa Fe in the CONMEBOL Sudamericana 2026: results, squad and schedule
Eduardo Coudet's side, winners of the trophy in 2014, topped their group in commanding fashion and strengthened the squad with several high-profile signings ahead of the knockout stage of 'La Gran Conquista'. This will be the ninth meeting between the two teams in CONMEBOL competitions, with the historical record favouring the Argentine side, who have four wins and four draws.
River Plate in the CONMEBOL Sudamericana 2026: results, squad and schedule
Match details
Stadium: Nemesio Camacho El Campín, Bogotá.
Kick-off: Temporarily suspended. Further information regarding the rescheduling will be provided shortly
Referee: Jesús Valenzuela (VEN).
VAR: Carlos Orbe (ECU).
Match facts:
- Independiente Santa Fe and River have met eight times in CONMEBOL competitions, with 'El Millonario' remaining unbeaten in the head-to-head record with four wins and four draws. Their only previous knockout meeting came in the 2016 Recopa, when the Argentine club lifted the trophy after a 2-1 aggregate victory.
- If Santa Fe defeat River in this match, they will equal their longest winning streak in CONMEBOL competition history at four consecutive victories, matching the runs they achieved in the 1999 Copa Merconorte and the 2013 Libertadores.
- Sebastián Driussi scored in the last knockout tie against Independiente Santa Fe, when he faced them with River in the 2016 CONMEBOL Recopa. The 'Millonario' forward has played only two matches in the current Sudamericana, but has scored in both, against Carabobo and Blooming.
- Eleven of River's last 14 goals against Colombian teams in CONMEBOL competitions have come from set pieces, including six from corners. The most recent was against Santa Fe in 2021, scored by Julián Álvarez.
- Hugo Rodallega has scored four goals in his last five CONMEBOL competition appearances and has eight since returning to Santa Fe. Two of those goals came in his two home matches against Argentine opposition: against Gimnasia in the 2023 Sudamericana and Platense in the 2026 Libertadores.
Santos vs. Macará
'Peixe' head into the first leg of their Round of 16 tie full of confidence. They scored eight goals across their two Playoff matches, with every member of their attacking unit making an impact and underlining both the depth and potential available to Cuca. Santos also boast a perfect record in previous Round of 16 ties against Ecuadorian opposition in CONMEBOL competitions, having eliminated Liga de Quito in the 2004 and 2020 CONMEBOL Libertadores.
Santos in the CONMEBOL Sudamericana 2026: results, squad and schedule
Surprise package Macará, winners of Group A, travel to Vila Belmiro looking to preserve their unbeaten record in the current CONMEBOL Sudamericana. Driven by their own growing belief, the Ambato side know they have enough weapons to challenge an opponent with major pedigree and history on the continental stage. Guillermo Sanguinetti's team have spent only 45 minutes trailing throughout the entire competition.
Macará in the CONMEBOL Sudamericana 2026: results, squad and schedule
Match details
Stadium: Urbano Caldeira (Vila Belmiro), Santos.
Kick-off: Thursday, August 13 - 7:00 p.m. (local time).
Referee: Kevin Ortega (PER).
VAR: Joel Alarcón (PER).
Match facts:
- Santos have won both Round of 16 ties they have played against Ecuadorian opposition in CONMEBOL competitions, both against Liga de Quito in the Libertadores (2004 and 2020).
- Macará remain unbeaten in the CONMEBOL Sudamericana 2026 (3 wins, 4 draws). The Ambato side have conceded only three goals so far, giving them the ninth-lowest goals-conceded average per match (0.43) by any team in a single edition of the competition among those to have played at least seven matches that season.
- Santos recorded the most elaborate attacks — defined as moves featuring more than 10 passes before the shot — during the CONMEBOL Sudamericana 2026 Group Stage, with 18, although none resulted in a goal for 'Peixe'.
- Gabigol has scored four goals in the CONMEBOL Sudamericana 2026. It is his highest tally in a single CONMEBOL competition since scoring six times in the 2022 Libertadores, which he won with Flamengo and in which he also scored in the Final.
- Macará spent the second-most minutes with the score level during the CONMEBOL Sudamericana 2026 Group Stage, with 405. They were also behind for only 45 minutes, which came in a 2-2 home draw against Tigre.
Vasco da Gama vs. Olimpia
Vasco da Gama and Olimpia will renew a matchup that already brought them together in the Group Stage of the current CONMEBOL Sudamericana. The memory of their meeting in Rio de Janeiro favors 'Cruzmaltino', who claimed a 3-0 victory.
The Brazilian side faced Independiente Medellín in the Playoffs: they first secured an important 2-2 draw away from home before backing it up with a 1-0 victory in the return leg.
Vasco da Gama in the CONMEBOL Sudamericana 2026: results, squad and schedule
The Paraguayan side will therefore travel to Brazil knowing that a positive away result could prove decisive in the tie, having already beaten Vasco 3-1 at the Defensores del Chaco on Matchday 5. 'El Decano', coached by Argentine manager Pablo Sánchez, produced an impressive Group Stage campaign and showed an ability to respond even in difficult situations: of the four matches in which they conceded first in the current edition, they came back to win three.
Olimpia in the CONMEBOL Sudamericana 2026: results, squad and schedule
Match details
Stadium: São Januário, Rio de Janeiro.
Kick-off: Thursday, August 13 - 7:00 p.m. (local time).
Referee: Darío Herrera (ARG).
VAR: Germán Delfino (ARG).
Match facts:
- Olimpia's Juan Alfaro was the player involved in the most team sequences that ended in goals during the CONMEBOL Sudamericana 2026 Group Stage, with six, level with RB Bragantino's Fernando.
- Vasco and Olimpia have faced each other four times in CONMEBOL competitions, including two meetings in the Group Stage of the current Sudamericana, but have never met in a knockout round. Both teams have won their two home matches in the head-to-head record.
- Vasco have a perfect home record against Paraguayan opposition in CONMEBOL competitions, winning all six matches they have played. They averaged 2.7 goals per game across those fixtures.
- Olimpia fell behind in four different matches in the CONMEBOL Sudamericana 2026 and came back to win three of them. No other team have recorded as many victories after conceding the opening goal in the current competition as 'El Franjeado'. One of those wins came against Vasco, 3-1, in the Group Stage.
- Since the Group Stage, Olimpia (16.4 metres) and Vasco (16.9 metres) rank among the five teams with the shortest average shooting distance in the CONMEBOL Sudamericana 2026.
Cienciano vs. Botafogo
Cienciano produced one of those unforgettable cup performances in the Playoffs. The Peruvian side eliminated reigning CONMEBOL Sudamericana champions Lanús after overturning a 2-0 first-leg deficit, sparking wild celebrations among the crowd at the Estadio Inca Garcilaso de la Vega. With a favorable home record against Brazilian opposition — just two defeats in six such matches — Cienciano will once again look to summon their cup spirit against a Botafogo side that enjoyed a solid Group Stage campaign.
Cienciano in the CONMEBOL Sudamericana 2026: results, squad and schedule
With Danilo Santos as one of their main scoring threats — he has three goals in the current competition — Botafogo will look to extend a remarkable record against Peruvian opposition: they have won all six of their matches against teams from Peru in CONMEBOL competitions.
Botafogo in the CONMEBOL Sudamericana 2026: results, squad and schedule
Match details
Stadium: Inca Garcilaso de la Vega, Cusco.
Kick-off: Thursday, August 13 - 7:30 p.m. (local time).
Referee: Augusto Aragón (ECU).
VAR: Franklin Congo (ECU).
Match facts:
- Cienciano have won three of their six home matches against Brazilian opposition in CONMEBOL competitions (1 draw, 2 losses), including the only one played in a knockout round: a 2-1 victory over Santos in the second leg of the 2003 CONMEBOL Sudamericana quarterfinals.
- Botafogo have won all six matches they have played against Peruvian opposition in CONMEBOL competitions, all of them in the Group Stage. Among CONMEBOL member nations, Peru is the only one against whose clubs Botafogo hold a 100% winning record in continental competition.
- Cristian Souza (Cienciano) created the most shooting opportunities for teammates following ball carries during the CONMEBOL Sudamericana 2026 Group Stage, with eight, one of which resulted in an assist.
- Alejandro Hohberg (Cienciano) has scored three goals from outside the box in the CONMEBOL Sudamericana 2026. Since 2013, no player has scored more goals from outside the area in a single edition of the competition.
- Danilo Santos is Botafogo's leading scorer in CONMEBOL competitions this season, with three goals. Including his spell with Palmeiras, the midfielder has scored eight times in continental competition, and his team have never lost when he has found the net (7 wins, 1 draw).